Histological reactions produced by experimental inoculation of Mycobacterium leprae murium into the golden hamster (Cricetus auratus).
نویسندگان
چکیده
Experimental inoculation of Mycobact erium lepme murium into the golden hamster, first done by Balfour-Jones, produces a generalized infection of slow but progressive evolution, with lesions in various organs (2,4,14,15). The Chinese hamster, however, is apparently not susceptible to this infection (13). Observations on this infection of the hamster have been mainly from the bacteriological point of view. The pathology of the disease produced, and particularly the histological reactions, have seldom been considered; only some gross changes and a few notes about microscopic lesions have been published (14, 15 ) . Nothing has been said about the cytogenesis, morphology, or functional behavior of the cells in the lesions, features which are of great value in defining the type of the tissue reaction produced by the mycobacteria (6,7). The present study deals with some of the cytological characters of the lesions. .
منابع مشابه
Histiocytic granulomatous mycobacterial lesions produced in the golden hamster (Cricetus auratus) inoculated with human leprosy: negative results in experiments using other animals.
In January 1956 a cooperative project was undertaken between the Armed Forces Institute of Pathology, Washington, D.C., and the U.S.P.H.S. Communicable Disease Center, Laboratory Branch, Chamblee, Georgia, for the purpose of attempting to infect laboratory animals with Mycobacterium leprae. To date more . than 35 inoculation experiments with M. leprae have been undertaken in approximately 1,500...
متن کاملHematological Findings in the Golden Hamster (cricetus Auratus)
Values for hemoglobin, erythrocytes, volume of packed cells, leucocytes, and their distribution, and red blood cell diameter are presented as determined on a group of 114 hamsters of both sexes and of various ages.
متن کاملThe ultrastructure of implantation in the golden hamster (Cricetus auratus).
Previous work on the early development of the golden hamster includes the investigation of Ochs (1908), Graves (1945) and Ward (1948), all at the level of the light microscope. Austin (1963) has examined the ultrastructure of the oocytes of the golden hamster while Enders & Schlafke (1965) have observed the pre-implantation stages of pregnancy. The ultrastructure of implantation has been studie...
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عنوان ژورنال:
- International journal of Leprosy
دوره 24 3 شماره
صفحات -
تاریخ انتشار 1956